p-Fluoro benzoylbutanoic acid

p-Fluoro benzoylbutanoic acid

CAS No.: 149437-76-3
Molecular Formula: C₁₁H₁₁FO₃
Molecular Weight: 210.20
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
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Product Description

4-(4-Fluorobenzoyl)butyric acid is a key pharmaceutical intermediate primarily used in the synthesis of cholesterol absorption inhibitors like ezetimibe. This compound exhibits a melting point of 142-144°C and boiling point of 394.6±22.0°C at 760 mmHg, with a density of 1.2±0.1 g/cm³. The material should be stored in sealed containers at room temperature, protected from moisture. Safety precautions include wearing protective gloves and eye/face protection due to potential skin/eye irritation (GHS Category 2). Its molecular structure containing both fluorobenzoyl and carboxylic acid functionalities makes it valuable for constructing bioactive molecules with improved metabolic stability.

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