4-Hydroxy-3-methylacetophenone is a phenolic ketone compound with significant antioxidant properties, originally isolated from green coffee beans (Coffea arabica L.). This compound demonstrates a melting point of 107-109°C and boiling point of 301.6±22.0°C at 760 mmHg. With a density of 1.1±0.1 g/cm³ and pKa of 8.52±0.18, it serves as a key intermediate for synthesizing antimycobacterial heterocycles. The material is slightly soluble in chloroform and methanol, and should be stored under inert atmosphere at room temperature. Safety precautions include wearing protective gloves due to potential skin irritation (GHS Category 2). Its structural features enable applications in fragrance formulations and medicinal chemistry.
