Ethyl 2-(methylthio) pyrimidine-5-carboxylate

Ethyl 2-(methylthio) pyrimidine-5-carboxylate

2-(methylthio)-5-pyrimidinecarboxylate
CAS No.: 73781-88-1
Molecular Formula: C₈H₁₀N₂O₂S
Molecular Weight: 198.24
Appearance: White to off-white crystalline powder
Purity: ≥95% (HPLC)
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Product Description

Ethyl 2-(methylthio)-5-pyrimidinecarboxylate is a key heterocyclic building block extensively used in pharmaceutical synthesis, particularly for antiviral and antitumor agents. This compound features a melting point of 38-40°C and boiling point of 313.5±15.0°C at 760 mmHg, with a predicted density of 1.24±0.1 g/cm³. The pyrimidine core with methylthio and ester functionalities makes it valuable for nucleoside analog synthesis. Storage should be in sealed containers at 2-8°C, protected from light and moisture. Safety precautions include wearing protective gloves/eyewear due to potential irritation (GHS Category 2). Its structural features enable diverse transformations in medicinal chemistry applications.

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