2-Fluoro thiobenzamide

2-Fluoro thiobenzamide

CAS No.: 75907-82-3
Molecular Formula: C₇H₆FNS
Molecular Weight: 155.19
Appearance: Yellow crystalline solid
Purity: ≥98% (HPLC)
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Product Description

2-Fluorothiobenzamide is a fluorinated thiobenzamide derivative primarily used as a pharmaceutical intermediate in the synthesis of bioactive molecules. The compound exhibits a melting point of 80-84°C and predicted boiling point of 240.6°C at 760 mmHg. With a density of 1.434±0.06 g/cm³ and pKa of 11.83±0.29, it demonstrates characteristic thioamide reactivity. Storage should be in sealed containers at 2-8°C under inert atmosphere. Safety precautions are required due to its harmful properties (GHS Category 6.1), including skin/eye irritation potential. The fluorine substitution at the ortho-position enhances its utility in medicinal chemistry applications, particularly for constructing fluorinated heterocycles.

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