3-Bromoanisole (m-Bromoanisole) is a brominated aromatic ether widely used as a pharmaceutical intermediate, notably in the synthesis of the analgesic drug Tramadol. This compound exhibits a boiling point of 210-211°C (100 kPa) with a density of 1.477 g/cm³ and refractive index of 1.5635. It is soluble in organic solvents (ethanol, ether, benzene) but insoluble in water. Storage should be in tightly sealed containers protected from light at room temperature. Safety precautions include wearing protective gloves/eyewear due to potential skin/eye irritation (GHS Category 2). The bromine and methoxy groups at meta-positions enable diverse electrophilic substitution reactions for further functionalization.
