3-Bromo-2-nitrothiophene

3-Bromo-2-nitrothiophene

CAS No.: 24430-27-1
Molecular Formula: C₄H₂BrNO₂S
Molecular Weight: 208.03
Appearance: Light yellow to yellow crystalline powder
Purity: ≥96% (HPLC)
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Product Description

3-Bromo-2-nitrothiophene is a halogenated nitrothiophene derivative widely used as a key intermediate in pharmaceutical synthesis, particularly for antithrombotic and antimicrobial agents. The compound exhibits a melting point of 79-81°C (hexane recrystallized) and boiling point of 228.6±20.0°C at 760 mmHg (predicted). With a density of 1.945±0.06 g/cm³ and refractive index of 1.672, it should be stored at 2-8°C under inert atmosphere due to light sensitivity. Safety precautions include wearing protective gloves/eyewear (GHS Category 2) as it may cause skin/eye irritation. Its molecular structure enables diverse transformations in heterocyclic chemistry, especially in Suzuki coupling and nucleophilic substitution reactions.

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