2-Chlorothiophene-5-formic acid

2-Chlorothiophene-5-formic acid

CAS No.: 24065-33-6
Molecular Formula: C₅H₃ClO₂S
Molecular Weight: 162.59
Appearance: Light yellow powder
Purity: ≥98% (HPLC)
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Product Description

2-Chlorothiophene-5-carboxylic acid is a crucial pharmaceutical intermediate, primarily used in the synthesis of rivaroxaban (a direct Factor Xa inhibitor anticoagulant). This heterocyclic compound features a melting point of 146-150°C and boiling point of 287°C at 760 mmHg. With a pKa of 3.32±0.10, it exhibits slight solubility in DMSO and methanol. The material should be stored in dry, dark conditions at room temperature. Safety precautions include wearing protective gloves and eyewear due to potential irritation (GHS Category 2).

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