2-Mercaptothiophene is a sulfur-containing heterocyclic compound with a strong burnt/rubbery odor. This reactive thiol derivative shows a boiling point of 166.9±13.0°C at 760 mmHg and density of 1.252 g/cm³ (25°C). It serves as a key intermediate for:
Pharmaceutical synthesis (e.g., cephalosporin antibiotics)
Organic electronic materials
Flavor/fragrance formulations
The compound oxidizes readily in air and should be stored under nitrogen at 2-8°C. Safety precautions include using chemical-resistant gloves (neoprene/nitrile) due to skin irritation (GHS Category 2) and operating in fume hoods to avoid inhalation exposure.
