2-Amino-3-cyano-5-methylthiophene is a key heterocyclic intermediate primarily used in the synthesis of olanzapine (an antipsychotic drug) and its related impurities. This compound features a melting point of 101-103°C and predicted boiling point of 318.5±42.0°C at 760 mmHg. With a density of 1.26±0.1 g/cm³ and LogP value of 2.09, it demonstrates good solubility in methanol. The material should be stored under inert gas (nitrogen/argon) at 2-8°C due to air sensitivity. As a versatile building block, its amino and cyano groups enable diverse transformations in medicinal chemistry. Safety precautions include wearing protective equipment as it may cause eye/skin irritation (GHS Category 2).
