1-benzothiophene-3-carbaldehyde

1-benzothiophene-3-carbaldehyde

CAS No.: 5381-20-4
Molecular Formula: C₉H₆OS
Molecular Weight: 162.21
Appearance: Yellow to pale brown crystalline powder
Purity: ≥98% (HPLC)
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Product Description

3-Formylbenzothiophene is an important heterocyclic aldehyde widely used as a pharmaceutical intermediate for synthesizing thrombin inhibitors and kinase modulators. This compound exhibits a melting point of 53-57°C (lit.) and boiling point of 166°C at 20 mmHg, with a density of 1.212 g/cm³ (estimate). The material should be stored sealed in dry conditions at 2-8°C, protected from light. As an aldehyde-functionalized benzothiophene derivative, it serves as a versatile building block for medicinal chemistry, particularly in the development of CNS-active compounds. Safety precautions include wearing protective gloves/eyewear due to potential irritation (GHS Category 2).

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