2-Chloro-5-bromo thiophene

2-Chloro-5-bromo thiophene

CAS No.: 2873-18-9
Molecular Formula: C₄H₂BrClS
Molecular Weight: 197.48
Appearance: Colorless to pale yellow liquid
Purity: ≥98% (GC)
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Product Description

2-Chloro-5-bromothiophene is a halogenated heterocyclic compound primarily used as a key intermediate in pharmaceutical and agrochemical synthesis. This compound has a boiling point of 69-70°C at 18 mmHg (lit.) and density of 1.803 g/mL at 25°C. It features high reactivity at both the 2- and 5-positions of the thiophene ring, making it valuable for cross-coupling reactions. The material should be stored under inert gas (nitrogen/argon) at 2-8°C, protected from light and moisture. Safety precautions include wearing chemical-resistant gloves and eye protection due to its irritant properties (GHS Category 2). Its applications include synthesis of thrombin inhibitors and photochromic materials.

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