![3-Bromomethyl-7-chlorobenzo[b]thiophene](/upload/20251022/812365088e46587d45ef804d938ecba5.png)
3-Bromomethyl-7-chlorobenzo[b]thiophene is a key pharmaceutical intermediate, notably serving as the core structure in Sertaconazole Nitrate synthesis. This heterocyclic compound exhibits a melting point of 116-120°C and predicted boiling point of 345.5±27.0°C at 760 mmHg, with a density of 1.693±0.06 g/cm³. It shows slight solubility in chloroform and methanol (with sonication). As an EP impurity standard (Sertaconazole EP Impurity B), it requires storage at 2-8°C in sealed containers. Safety precautions include using personal protective equipment due to its corrosive/harmful properties (GHS Category 2). The bromomethyl group at the 3-position enables versatile functionalization in medicinal chemistry.
