2-Bromo-5-methylthiophene is a halogenated heterocyclic compound widely used as a pharmaceutical intermediate and organic synthesis building block. This thiophene derivative exhibits a boiling point of 65°C (15 mmHg) with a density of 1.552 g/cm³ at 25°C and refractive index of 1.569. The compound demonstrates enhanced reactivity at the 2-position for electrophilic substitution reactions due to its aromatic thiophene ring. Storage should be in sealed containers under inert atmosphere (nitrogen/argon) at 2-8°C, stabilized with copper chips (0.1%) and sodium bicarbonate (0.4%) to prevent decomposition. Safety precautions include wearing chemical-resistant gloves and eye protection due to potential skin/eye irritation (GHS Category 2).
