2-Bromothiophene is an important halogenated heterocyclic compound widely used as a pharmaceutical intermediate (e.g., for clopidogrel synthesis) and organic building block. This liquid exhibits a boiling point of 149-151°C, density of 1.684 g/cm³ (25°C), and refractive index of 1.586 (20°C). It is soluble in organic solvents like ether/acetone but insoluble in water. The compound should be stored in cool, well-ventilated areas away from oxidizers. Safety precautions include wearing chemical-resistant gloves and eye protection due to its irritating properties (GHS Category 2). Its bromine substituent at the 2-position enables diverse cross-coupling reactions (e.g., Suzuki, Stille) for thiophene derivative synthesis.
