Benzylsulfonamide is a versatile sulfonamide compound widely used as a protecting group reagent in organic synthesis and pharmaceutical intermediates. It exhibits a melting point of 103-105°C and boiling point of 343.1±35.0°C (predicted), with a density of 1.312±0.06 g/cm³. The compound is soluble in ethanol and ether but slightly soluble in cold water. As an important building block, it demonstrates protective effects for amino groups during chemical transformations. Storage should be in sealed containers at room temperature, protected from moisture. Safety precautions include wearing protective gloves/eyewear due to potential irritation (GHS Category 2). Its sulfonamide moiety enables diverse applications in peptide chemistry and drug discovery.
