2-Fluorophenyl methyl sulfone (o-Fluorophenyl methyl sulfone) is a fluorinated aromatic sulfone compound primarily used as a pharmaceutical intermediate in synthesizing glucokinase activators and other bioactive molecules. This compound has a melting point of 48-52°C and boiling point of 304.5±34.0°C at 760 mmHg, with a density of 0.975 g/cm³ and refractive index of 1.507. It should be stored sealed in dry conditions at room temperature. Safety precautions include wearing protective gloves/eyewear due to potential skin/eye irritation (GHS Category 2). The ortho-fluorine substitution enhances its reactivity in nucleophilic aromatic substitution reactions, making it valuable for constructing complex drug molecules.
