2-Bromobenzenesulfonamide (o-Bromobenzenesulfonamide) is a versatile sulfonamide derivative extensively used in pharmaceutical synthesis and organic transformations. This compound exhibits a melting point of 191-195°C (lit.) and predicted boiling point of 374.5±44.0°C at 760 mmHg. With a density of 1.754±0.06 g/cm³ and pKa of 9.66±0.60, it serves as a key intermediate for heterocyclic compounds and bioactive molecules. The material is stable under normal conditions but should be protected from moisture. Safety precautions include wearing protective gloves/eyewear due to potential irritation (GHS Category 2). Its molecular structure enables diverse transformations including intramolecular arylation reactions under transition metal-free conditions.
