4-Fluorophenyl methyl sulfone

4-Fluorophenyl methyl sulfone

CAS No.: 455-15-2
Molecular Formula: C₇H₇FO₂S
Molecular Weight: 174.19
Appearance: White to off-white crystalline powder
Purity: ≥98% (GC)
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Product Description

4-Fluorophenyl methyl sulfone is a key fluorinated aromatic sulfone compound widely used as a pharmaceutical intermediate, notably in the synthesis of bicalutamide API and other bioactive molecules. It exhibits a melting point of 78-81°C (lit.) and boiling point of 295.9±32.0°C at 760 mmHg. The compound has a density of 1.3±0.1 g/cm³ and refractive index of 1.507. Storage should be in sealed dry conditions at room temperature. Safety precautions include wearing protective equipment due to potential irritation to eyes/skin (GHS Category 2). Its sulfone group and fluorine substitution make it valuable for constructing drug molecules with enhanced metabolic stability.

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