5-Chloro-2-thiophenesulfonyl chloride is a sulfonyl chloride derivative primarily used as a key intermediate in pharmaceutical synthesis, notably for antiplatelet drugs like ENOGREN. It exhibits moisture sensitivity and reacts violently with water, releasing HCl gas. Typical storage conditions recommend sealing under inert gas (nitrogen/argon) at 2–8°C. The compound has a density of 1.623 g/cm³ (25°C), boiling point of 112–117°C (lit.), and flash point of 110°C. Safety measures include corrosion-resistant PPE due to its skin/eye corrosion hazards (GHS Category 1B).
