2-Bromophenyl ethyl sulfide is an aromatic thio-ether in which a bromine atom is located ortho to the sulfur bridge on the phenyl ring. The compound is air-stable, freely miscible with common organic solvents (dichloromethane, ethyl acetate, toluene, alcohols) and essentially insoluble in water. Commercial material is supplied ≥98 % pure.
Key physicochemical data:
Density: 1.40 ± 0.1 g cm⁻³ (20 °C)
Refractive index n²⁰/D: 1.607
Boiling point: 248 ± 23 °C / 760 mmHg
Flash point: 104 ± 23 °C
Log P (octanol/water): 4.2 (predicted)
Typical uses:
Versatile building block for ortho-bromo-phenyl sulfoxides/sulfones used in pharmaceutical and agro-chemical synthesis.
Precursor for benzo[b]thiophene derivatives via intramolecular cyclisation or cross-coupling protocols.
Model substrate for mechanistic studies on electron-deficient C–S bond activation and radical generation.
Quality specification (commercial grade):
Purity (GC): ≥98 %
Water content (KF): ≤0.2 %
Free thiol (as PhSH): ≤0.1 %
Residue on ignition: ≤0.1 %
Heavy metals: ≤20 ppm
Hazard statement:
Causes skin and eye irritation (H315 + H319). Avoid inhalation of vapour; use gloves, goggles and adequate ventilation. Store in a cool, dry place away from oxidants. SDS available on request.
