3,3'-Thiodipropionic acid dimethyl ester is a bifunctional aliphatic thio-ester containing two methyl propionate units linked by a sulfur atom. It is air-stable, miscible with most organic solvents, and practically insoluble in water. Commercial material is supplied ≥98 % pure .
Key physicochemical data:
Density: 1.198 g cm⁻³ (25 °C)
Refractive index: n²⁰/D 1.475
Boiling point: 148 °C / 18 mmHg
Flash point: >110 °C
Log P (octanol/water): 1.9 (predicted)
Typical uses:
High-purity building block for poly(thio-ester)s and antioxidant plastic additives .
Precursor for UV-curable coatings, lubricant antioxidants and sulfur-containing pharmaceutical intermediates.
Model substrate for enzymatic esterification and transesterification studies .
Quality specification (commercial grade):
Purity (GC): ≥98 %
Water content (KF): ≤0.2 %
Free acid (as thiodipropionic acid): ≤0.5 %
Residue on ignition: ≤0.1 %
Heavy metals: ≤20 ppm
Hazard statement:
Causes skin and eye irritation (H315 + H319). Avoid inhalation of vapour; use gloves, goggles and adequate ventilation. Store in a cool, dry place away from oxidants and strong bases. SDS available on request .
