3,5-Dichlorophenylthioethanol is an aromatic thio-ether bearing two chlorine atoms meta to the sulfur bridge and a terminal hydroxyl group. It is air-stable, freely soluble in dichloromethane, ethyl acetate, ethanol and toluene, and practically insoluble in water. Commercial product is supplied ≥95.5 % pure .
Key physicochemical data:
Refractive index n²⁰/D: 1.621
Predicted b.p.: 340 °C / 760 mmHg
Flash point: >110 °C
Log P (octanol/water): 4.0 (predicted)
Typical uses:
Versatile building block for 3,5-dichloro-phenyl-thio-ethyl ethers, sulfoxides and sulfones used in pharmaceutical and agro-chemical synthesis.
Precursor for UV-curable monomers, polymer-chain transfer agents and antioxidant additives.
Model substrate for mechanistic studies on electron-deficient C–S bond activation and cross-coupling reactions.
Quality specification (commercial grade):
Purity (GC): ≥95.5 %
Water content (KF): ≤0.3 %
Free thiol (as 3,5-Cl₂-PhSH): ≤0.2 %
Residue on ignition: ≤0.1 %
Heavy metals: ≤20 ppm
Hazard statement:
Causes skin and eye irritation (H315 + H319). Avoid inhalation of vapour; use gloves, goggles and adequate ventilation. Store in a cool, dry place away from oxidants. SDS available on request.
