2,4,6-Trimethyl diphenyl sulfide is a highly hindered aromatic thio-ether carrying three methyl groups at positions 2, 4 and 6 of the phenyl ring directly attached to sulfur. The material is air- and photo-stable, miscible with all common organic solvents (dichloromethane, chloroform, ethyl acetate, toluene, alcohols, ketones) and essentially insoluble in water (≤1 mg L⁻¹ at 25 °C).
Key physicochemical data:
Melting point: 36–38 °C
Boiling point: 325 °C / 760 mmHg (predicted)
Density: 1.01 g cm⁻³ (40 °C, liquid)
Refractive index n²⁰/D: 1.57
Flash point: > 140 °C
Log P (octanol/water): 5.7 (predicted)
Typical uses:
High-boiling, low-volatility solvent and heat-transfer fluid for engineering plastics and polyimide processing.
Sterically hindered building block for 2,4,6-trimethyl-diphenyl sulfoxide/sulfone high-temperature plasticisers and flame retardants.
Model substrate for mechanistic studies on sterically encumbered C–S bond activation and cross-coupling reactions.
Quality specification (commercial grade):
Purity (GC): ≥98 %
Water content (KF): ≤0.2 %
Free thiol (as PhSH): ≤0.1 %
Residue on ignition: ≤0.1 %
Heavy metals: ≤20 ppm
Hazard statement:
Causes skin and eye irritation (R36/37/38). Avoid inhalation of vapour or dust; use gloves, goggles and adequate ventilation. SDS available on request.
