2,5-Dimethoxy thiophenol

2,5-Dimethoxy thiophenol

CAS No.: 1483-27-8
Molecular Formula: C₈H₁₀O₂S
Molecular Weight: 170.23 g mol⁻¹
Appearance: colourless to pale-yellow clear oil; fp 122 °C, bp 88–90 °C/0.5 mmHg, nD²⁰ 1.586, ρ 1.134 g cm⁻³
Purity: ≥98.5 % (GC)
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Product Description

A bifunctional aromatic thiol bearing two strongly electron-donating methoxy groups (pKₐ 6.4). It is a key building block for:
High-refractive-index poly(aryl sulfide) resins (nD ≈ 1.68) used in 5G lens substrates and OLED encapsulation films;
Electron-rich aryl-sulfide ligands for Cu- or Pd-catalysed cross-couplings and photoredox transformations;
Self-assembled monolayers (SAMs) on gold, providing hydrophobic yet polar surfaces for SERS sensors and MEMS anti-stiction layers;
Synthesis of 2,5-dimethoxy-phenethyl thio-ethers employed as fragrance fixatives and antioxidant additives.
Store under nitrogen at 2–8 °C, protect from oxidants to prevent disulfide formation.

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